ruv (version 0.9.7.1)

Detect and Remove Unwanted Variation using Negative Controls

Description

Implements the 'RUV' (Remove Unwanted Variation) algorithms. These algorithms attempt to adjust for systematic errors of unknown origin in high-dimensional data. The algorithms were originally developed for use with genomic data, especially microarray data, but may be useful with other types of high-dimensional data as well. These algorithms were proposed in Gagnon-Bartsch and Speed (2012) , Gagnon-Bartsch, Jacob and Speed (2013), and Molania, et. al. (2019) . The algorithms require the user to specify a set of negative control variables, as described in the references. The algorithms included in this package are 'RUV-2', 'RUV-4', 'RUV-inv', 'RUV-rinv', 'RUV-I', and RUV-III', along with various supporting algorithms.

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Install

install.packages('ruv')

Monthly Downloads

1,295

Version

0.9.7.1

License

GPL

Last Published

August 30th, 2019

Functions in ruv (0.9.7.1)