Han Chen

Han Chen

4 packages on CRAN

mvtmeta

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This package contains functions to run fixed effects or random effects multivariate meta-analysis.

rareGE

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Tests gene-environment interaction for rare genetic variants using Sequence Kernel Association Test (SKAT) type gene-based tests. Includes two tests for the interaction term only, and one joint test for genetic main effects and gene-environment interaction.

seqMeta

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Computes necessary information to meta analyze region-based tests for rare genetic variants (e.g. SKAT, T1) in individual studies, and performs meta analysis.

aGE

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Tests gene-environment interaction for rare genetic variants within the framework of adaptive sum of powered score test. The package includes two tests: adaptive gene-by-environment interaction test, and joint test for genetic main effects and gene-environment interaction. See Yang et al (2018) <doi:10.1002/sim.8037>.