Sheeja Manchira Krishnan
3 packages on CRAN
Basic checks needed with an individual level participant data from randomised controlled trial. This checks files for existence, read access and individual columns for formats. The checks on format is currently implemented for gender and age formats.
A collection of functions to construct Markov model for model-based cost-effectiveness analysis. This includes creating Markov model (both time homogenous and time dependent models), decision analysis, sensitivity analysis (deterministic and probabilistic). The package allows estimation of parameters for the Markov model from a given individual patient level data, provided the data file follows some standard data entry rules.
EQ-5D is a standard instrument (<https://euroqol.org/eq-5d-instruments/>) that measures the quality of life often used in clinical and economic evaluations of health care technologies. Both adult versions of EQ-5D (EQ-5D-3L and EQ-5D-5L) contain a descriptive system and visual analog scale. The descriptive system measures the patient's health in 5 dimensions: the 5L versions has 5 levels and 3L version has 3 levels. The descriptive system scores are usually converted to index values using country specific values sets (that incorporates the country preferences). This package allows the calculation of both descriptive system scores to the index value scores. The value sets for EQ-5D-3L are from the references mentioned in the website <https://euroqol.org/eq-5d-instruments/eq-5d-3l-about/valuation/> The value sets for EQ-5D-3L for a total of 31 countries are used for the valuation (see the user guide for a complete list of references). The value sets for EQ-5D-5L are obtained from references mentioned in the <https://euroqol.org/eq-5d-instruments/eq-5d-5l-about/valuation-standard-value-sets/> and other sources. The value sets for EQ-5D-5L for a total of 17 countries are used for the valuation (see the user guide for a complete list of references). The package can also be used to map 5L scores to 3L index values for 10 countries: Denmark, France, Germany, Japan, Netherlands, Spain, Thailand, UK, USA, and Zimbabwe. The value set and method for mapping are obtained from Van Hout et al (2012) <doi: 10.1016/j.jval.2012.02.008>.