Identifies differentially expressed genes between two groups of cells using the LRT model proposed in Mcdavid et al, Bioinformatics, 2011
DiffExpTest(object, cells.1, cells.2, genes.use = NULL, thresh.use = log(2),
print.bar = TRUE)Seurat object
Group 1 cells
Group 2 cells
Genes to test. Default is to use all genes.
Limit testing to genes which show, on average, at least X-fold difference (log-scale) between the two groups of cells. Default is 0.25 Increasing thresh.use speeds up the function, but can miss weaker signals.
Print a progress bar once expression testing begins (uses pbapply to do this)
Returns a p-value ranked matrix of putative differentially expressed genes.