as.ev

as.ev,data.frame-method

as.ev,ev-method

<p>if <code>TRUE</code>, <code>ID</code> column is retained if it exists</p>

keep_id

<p>if <code>TRUE</code>, only dosing or ID information is retained in
the result</p>

clean

Facilitates simulation from hierarchical, ordinary
differential equation (ODE) based models typically employed in drug development.
A model specification file is created consisting of R and C++ code that
is parsed, compiled, and dynamically loaded into the R session. Input data are
passed in and simulated data are returned as R objects.  A dosing event engine
allows interventions (bolus and infusion) to be managed separately from the
model code. Differential equations are solved with the 'DLSODA' routine
in 'ODEPACK' (<https://computation.llnl.gov/casc/odepack/>).

Kyle T Baron

mrgsolve

Simulate from ODE-Based Population PK/PD and Systems
Pharmacology Models

Alan C Hindmarsh

Linda R Petzold

Bill Gillespie

Charles Margossian

Devin Pastoor

Metrum Research Group LLC 

as.ev function

Coerce an object to class ev — as.ev

Coerce an object to class ev

as.ev: Coerce an object to class ev

Description

Usage

Arguments