Function event simulates the events base on a recruitment scenario simulated by function recruitment.
event(r, er, dr, du)recruitment scenario calculated with function recruitment.
event rate during the clinical trail.
drop-out rate during the clinical trail.
duration of the clinical trail in weeks.
event returns a list of vectors with the following components:
events a vector with the (cumulative) number of frist events (events before drop-out)
drops a vector with the (cumulative) number of patients who droped out of the trail before the first event
weeksOfEvent a vector with the corresponding trial week when patients have experienced the first event
(with start of site openings as reference start)
event simulates the events based on a given recruitment scenario.
The function assumes an exponential distribution for the event probability with a common event rate for all subjects (er).
The drop-out rate may be included. For the probability of an drop-out, treatment assumes an exponential distribution with a common rate dr.
It is assumed that the even and drop-out time are independent of each other.
recruitment for simulating recruitment scenarios;
eventCourse for plots of recruitment and event scenarios;
# NOT RUN {
x=recruitment(nc=Inf,ns=Inf,cw=4,sw=2,sf=0.3,tb=4,en=400)
y=event(r=x,er=0.12,dr=0.08,du=50)
x=recruitment(nc=Inf,ns=Inf,cw=4,sw=2,sf=0.3,tb=4,en=400)
y=event(r=x,er=0.12,dr=0.08,du=50)
# }
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