limma (version 3.28.6)

ids2indices: Convert Gene Identifiers to Indices for Gene Sets

Description

Make a list of gene identifiers into a list of indices for gene sets.

Usage

ids2indices(gene.sets, identifiers, remove.empty=TRUE)

Arguments

gene.sets

list of character vectors, each vector containing the gene identifiers for a set of genes.

identifiers

character vector of gene identifiers.

remove.empty

logical, should sets of size zero be removed from the output?

Value

• list of integer vectors, each vector containing the indices of a gene set in the vector identifiers.

Details

This function used to create input for romer, mroast and camera function. Typically, identifiers is the vector of Entrez Gene IDs, and gene.sets is obtained constructed from a database of gene sets, for example a representation of the Molecular Signatures Database (MSigDB) downloaded from http://bioinf.wehi.edu.au/software/MSigDB.

See Also

romer, mroast, camera There is a topic page on 10.GeneSetTests.

Examples

download.file("http://bioinf.wehi.edu.au/software/MSigDB/human_c2_v5.rdata", 
	      "human_c2_v5.rdata", mode = "wb")

load("human_c2_v5.rdata")
c2.indices <- ids2indices(Hs.c2, y$genes$GeneID)
camera(y, c2.indices, design)