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lumi (version 2.24.0)

lumiMethyN: Normalize the Illumina Infinium methylation data

Description

Normalize the Illumina Infinium methylation data, which is an object in MethyLumiM class.

Usage

lumiMethyN(methyLumiM, method = c("quantile", "ssn", "none"), separateColor = FALSE, verbose = TRUE, overwriteBigMatrix = FALSE, ...)

Arguments

methyLumiM
a MethyLumiM object includes Illumina Infinium methylation data
method
supported normalization methods or user provided function, whose input and output should be a intensity matrix (pool of methylated and unmethylated probe intensities)
separateColor
determine whether to separately process two color channels
verbose
a boolean to decide whether to print out some messages
overwriteBigMatrix
whether to overwrite the result to the BigMatrix data, only valid when the input data is BigMatrix-based
...
other parameters used by corresponding method

Value

Return an object (same class as input methyLumiM) with updated "methylated" and "unmethylated" data matrix after background level adjustment.

See Also

See Also normalizeMethylation.ssn and normalizeMethylation.quantile

Examples

Run this code
data(example.lumiMethy)
lumiMethy.norm = lumiN(example.lumiMethy)

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