Signac
Overview
Signac is a comprehensive R package for the analysis of single-cell chromatin data. Signac includes functions for quality control, normalization, dimension reduction, clustering, differential activity, and more.
Documentation and tutorials can be found at https://satijalab.org/signac/
Installation
Signac requires that Bioconductor is installed:
if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install()
setRepositories(ind=1:2)To install the latest release of Signac from CRAN:
install.packages("Signac")To release the latest develop version from GitHub:
if (!requireNamespace("remotes", quietly = TRUE))
install.packages("remotes")
remotes::install_github("timoast/signac", ref = "develop")Release notes
For a changelog please see the NEWS file, also available on the Signac website.
Getting help
If you encounter a bug or have a feature request, please open an issue.
If you would like to discuss questions related to single-cell analysis, you can open a discussion.
Citing Signac
If you use the Signac package in your work please cite Stuart et al. 2020
@UNPUBLISHED{signac,
title = "Multimodal single-cell chromatin analysis with Signac",
author = "Stuart, Tim and Srivastava, Avi and Lareau, Caleb and Satija,
Rahul",
journal = "bioRxiv",
pages = "2020.11.09.373613",
month = nov,
year = 2020,
url = "https://www.biorxiv.org/content/10.1101/2020.11.09.373613v1",
language = "en"
}