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meta (version 4.7-0)

metacor: Meta-analysis of correlations

Description

Calculation of fixed and random effects estimates for meta-analyses with correlations; inverse variance weighting is used for pooling.

Usage

metacor(cor, n, studlab, data=NULL, subset=NULL, sm=gs("smcor"), level=gs("level"), level.comb=gs("level.comb"), comb.fixed=gs("comb.fixed"), comb.random=gs("comb.random"), hakn=gs("hakn"), method.tau=gs("method.tau"), tau.preset=NULL, TE.tau=NULL, tau.common=gs("tau.common"), prediction=gs("prediction"), level.predict=gs("level.predict"), method.bias=gs("method.bias"), backtransf=gs("backtransf"), title=gs("title"), complab=gs("complab"), outclab="", byvar, bylab, print.byvar=gs("print.byvar"), byseparator = gs("byseparator"), keepdata=gs("keepdata") )

Arguments

cor
Correlation.
n
Number of observations.
studlab
An optional vector with study labels.
data
An optional data frame containing the study information, i.e., cor and n.
subset
An optional vector specifying a subset of studies to be used.
sm
A character string indicating which summary measure ("ZCOR" or "COR") is to be used for pooling of studies.
level
The level used to calculate confidence intervals for individual studies.
level.comb
The level used to calculate confidence intervals for pooled estimates.
comb.fixed
A logical indicating whether a fixed effect meta-analysis should be conducted.
comb.random
A logical indicating whether a random effects meta-analysis should be conducted.
prediction
A logical indicating whether a prediction interval should be printed.
level.predict
The level used to calculate prediction interval for a new study.
hakn
A logical indicating whether the method by Hartung and Knapp should be used to adjust test statistics and confidence intervals.
method.tau
A character string indicating which method is used to estimate the between-study variance $\tau^2$. Either "DL", "PM", "REML", "ML", "HS", "SJ", "HE", or "EB", can be abbreviated.
tau.preset
Prespecified value for the square-root of the between-study variance $\tau^2$.
TE.tau
Overall treatment effect used to estimate the between-study variance tau-squared.
tau.common
A logical indicating whether tau-squared should be the same across subgroups.
method.bias
A character string indicating which test is to be used. Either "rank", "linreg", or "mm", can be abbreviated. See function metabias
backtransf
A logical indicating whether results for Fisher's z transformed correlations (sm="ZCOR") should be back transformed in printouts and plots. If TRUE (default), results will be presented as correlations; otherwise Fisher's z transformed correlations will be shown.
title
Title of meta-analysis / systematic review.
complab
Comparison label.
outclab
Outcome label.
byvar
An optional vector containing grouping information (must be of same length as event.e).
bylab
A character string with a label for the grouping variable.
print.byvar
A logical indicating whether the name of the grouping variable should be printed in front of the group labels.
byseparator
A character string defining the separator between label and levels of grouping variable.
keepdata
A logical indicating whether original data (set) should be kept in meta object.

Value

An object of class c("metacor", "meta") with corresponding print, summary, plot function. The object is a list containing the following components:

Details

Fixed effect and random effects meta-analysis of correlations based either on Fisher's z transformation of correlations (sm="ZCOR") or direct combination of correlations (sm="COR") (see Cooper et al., p264-5 and p273-4).

Only few statisticians would advocate the use of untransformed correlations unless sample sizes are very large (see Cooper et al., p265). The artificial example given below shows that the smallest study gets the largest weight if correlations are combined directly because the correlation is closest to 1. For several arguments defaults settings are utilised (assignments using gs function). These defaults can be changed using the settings.meta function. Internally, both fixed effect and random effects models are calculated regardless of values choosen for arguments comb.fixed and comb.random. Accordingly, the estimate for the random effects model can be extracted from component TE.random of an object of class "meta" even if argument comb.random=FALSE. However, all functions in R package meta will adequately consider the values for comb.fixed and comb.random. E.g. function print.meta will not print results for the random effects model if comb.random=FALSE.

A prediction interval for treatment effect of a new study is calculated (Higgins et al., 2009) if arguments prediction and comb.random are TRUE.

R function update.meta can be used to redo the meta-analysis of an existing metacor object by only specifying arguments which should be changed.

For the random effects, the method by Hartung and Knapp (2003) is used to adjust test statistics and confidence intervals if argument hakn=TRUE. The DerSimonian-Laird estimate (1986) is used in the random effects model if method.tau="DL". The iterative Paule-Mandel method (1982) to estimate the between-study variance is used if argument method.tau="PM". Internally, R function paulemandel is called which is based on R function mpaule.default from R package metRology from S.L.R. Ellison .

If R package metafor (Viechtbauer 2010) is installed, the following methods to estimate the between-study variance $\tau^2$ (argument method.tau) are also available:

  • Restricted maximum-likelihood estimator (method.tau="REML")
  • Maximum-likelihood estimator (method.tau="ML")
  • Hunter-Schmidt estimator (method.tau="HS")
  • Sidik-Jonkman estimator (method.tau="SJ")
  • Hedges estimator (method.tau="HE")
  • Empirical Bayes estimator (method.tau="EB").

For these methods the R function rma.uni of R package metafor is called internally. See help page of R function rma.uni for more details on these methods to estimate between-study variance.

References

Cooper H, Hedges LV, Valentine JC (2009), The Handbook of Research Synthesis and Meta-Analysis, 2nd Edition. New York: Russell Sage Foundation. DerSimonian R & Laird N (1986), Meta-analysis in clinical trials. Controlled Clinical Trials, 7, 177--188. Higgins JPT, Thompson SG, Spiegelhalter DJ (2009), A re-evaluation of random-effects meta-analysis. Journal of the Royal Statistical Society: Series A, 172, 137--159. Knapp G & Hartung J (2003), Improved Tests for a Random Effects Meta-regression with a Single Covariate. Statistics in Medicine, 22, 2693--710, doi: 10.1002/sim.1482 .

Paule RC & Mandel J (1982), Consensus values and weighting factors. Journal of Research of the National Bureau of Standards, 87, 377--385.

Viechtbauer W (2010), Conducting Meta-Analyses in R with the Metafor Package. Journal of Statistical Software, 36, 1--48.

See Also

update.meta, metacont, metagen, print.meta

Examples

Run this code
m1 <- metacor(c(0.85, 0.7, 0.95), c(20, 40, 10))

#
# Print correlations (back transformed from Fisher's z transformation)
#
m1

#
# Print Fisher's z transformed correlations 
#
print(m1, backtransf=FALSE)

#
# Forest plot with back transformed correlations
#
forest(m1)

#
# Forest plot with Fisher's z transformed correlations
#
forest(m1, backtransf=FALSE)


m2 <- update(m1, sm="cor")
m2
# Identical forest plots (as back transformation is the identity transformation)
# forest(m2)
# forest(m2, backtransf=FALSE)

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