Estimates the net benefit and standardized net benefit of a risk score given a risk threshold R. Additionally estimates the standardized net benefit of a "treat-all" (everyone recieves intervention) treatment rule.
nb(y, p, r)Vector of binary outcomes, with 1 indicating event (case) and 0 indicating no event (controls)
Vector of risk score values
Clinically relevant risk threshold
Net benefit of risk score
Standardized net benefit of risk score
Standardized net benefit of a decision rule where everyone recieves treatment
Pauker, S. G., & Kassirer, J. P. (1980). The threshold approach to clinical decision making. New England Journal of Medicine, 302(20), 1109-1117.
Mishra, A. (2019). Methods for Risk Markers that Incorporate Clinical Utility (Doctoral dissertation). (Available Upon Request)