npde (version 2.0)

npde.decorr.method: Method used to decorrelate vectors

Description

Specifies the method used to decorrelate observed and simulated data

Arguments

Value

cholesky
decorrelation is performed through the Cholesky decomposition (default)
inverse
decorrelation is performed by inverting Vi through the eigen function
polar
the singular-value decomposition (svd) is used

Details

More details can be found in the PDF documentation.

References

K. Brendel, E. Comets, C. Laffont, C. Laveille, and F. Mentre. Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide. Pharmaceutical Research, 23:2036--49, 2006.