RnaSeqSampleSize (version 1.4.2)

sample_size: sample_size

Description

A function to estitamete the sample size for differential expression analysis of RNA-seq data.

Usage

sample_size(power = 0.8, m = 20000, m1 = 200, f = 0.1, k = 1, w = 1, rho = 2, lambda0 = 5, phi0 = 1, showMessage = FALSE, storeProcess = FALSE)

Arguments

power

Power to detecte prognostic genes.

m

Total number of genes for testing.

m1

Expected number of prognostic genes.

f

FDR level

k

Ratio of sample size between two groups.

w

Ratio of normalization factors between two groups.

rho

minimum fold changes for prognostic genes between two groups.

lambda0

Average read counts for prognostic genes.

phi0

Dispersion for prognostic genes.

showMessage

Logical. Display the message in the estimation process.

storeProcess

Logical. Store the power and n in sample size or power estimation process.

Value

Estimate sample size or a list including parameters and sample size in the process.

Details

A function to estitamete the sample size for differential expression analysis of RNA-seq data.

Examples

power<-0.8;rho<-2;lambda0<-5;phi0<-0.5;f<-0.01
sample_size(power=power, f=f,rho=rho, lambda0=lambda0, phi0=phi0)