simdurbin: Gene intensities simulator
Description
Simulates gene intensities from the two components model as in
the papers of Durbin and Rocke.Usage
simdurbin(n, alpha, mu, seta, seps)
Arguments
n
number of intensities to be simulated
alpha
background mean of gene intensities
mu
the means where the gene intensities are simulated from
seta
standard deviation of high-level gene intensities
seps
standard deviation of low-level gene intensities
Value
- A vector of the appropriate intensities.
Details
This function generates n intensities from the
Durbin and Rocke (2001) gene intensity model with parameters
alpha, seta and seps.References
Rocke, D.M. and Durbin, B.P. (2001), A model for measurement error for gene expression arrays, Journal of
Computational Biology, 8, 557-569