ADAPTS (version 0.9.21)

buildSpilloverMat: Build a spillover matrix, i.e. what do purified samples deconvolve as?

Description

spillExpr <- buildSpilloverMat(refExpr, geneExpr, method='DCQ')

Usage

buildSpilloverMat(refExpr, geneExpr, method = "DCQ")

Arguments

refExpr

The deconvolution matrix, e.g. LM22 or MGSM27

geneExpr

The full gene expression for purified cell types. Multiple columns (examples) for each column in the reference expr.

method

One of 'DCQ', 'SVMDECON', 'DeconRNASeq' (DEFAULT: DCQ)

Value

A spillover matrix showing how purified cell types deconvolve

Examples

# NOT RUN {
#This toy example 
library(ADAPTS)
fullLM22 <- ADAPTS::LM22[1:30, 1:4]
smallLM22 <- fullLM22[1:25,] 

spillover <- buildSpilloverMat(refExpr=smallLM22, geneExpr=fullLM22)
# }