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AGSDest (version 2.3.1)

Estimation in Adaptive Group Sequential Trials

Description

Calculation of repeated confidence intervals as well as confidence intervals based on the stage-wise ordering in group sequential designs and adaptive group sequential designs. For adaptive group sequential designs the confidence intervals are based on the conditional rejection probability principle. Currently the procedures do not support the use of futility boundaries or more than one adaptive interim analysis.

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Version

Install

install.packages('AGSDest')

Monthly Downloads

61

Version

2.3.1

License

GPL (>= 2)

Maintainer

Matthias Brueckner

Last Published

June 17th, 2016

Functions in AGSDest (2.3.1)

pvalue

Calculates the p-value
as.GST

as Group Sequential Trial
cer

Conditional type I error rate (also called conditional rejection probability)
AGSTobj

Adaptive group sequential trial object (AGSTobj)
AGSDest

Estimation in adaptive group sequential trials
as.AGST

as Adaptive Group Sequential Trial
adapt

Adaptations in group sequential trials
plan.GST

Plans a group sequential trial (GST)
GSTobj

Group sequential trial object (GSTobj)
cp

coditional power of a GSD
seqconfint

Calculates confidence interval
typeIerr

type I error rate of a GSD