get_ac_mat

simulation function: simulate allele count information for `n_var` variants, with a maximum allele count `max_cnt`

Provides statistical tools to analyze heterogeneous effects of rare variants within genes that are associated with multiple traits. The package implements methods for assessing pleiotropic effects and identifying allelic heterogeneity, which can be useful in large-scale genetic studies. Methods include likelihood-based statistical tests to assess these effects. For more details, see Lu et al. (2024) <doi:10.1101/2024.10.01.614806>.

Wenhan Lu

ALLSPICER

ALLelic Spectrum of Pleiotropy Informed Correlated Effects

get_ac_mat function

<dl><dt>n_var</dt>
<dd>total number of variants</dd>
<dt>max_cnt</dt>
<dd>maximum allele count, default 100</dd></dl>

Arguments

get_ac_mat — get_ac_mat

<dl>

<dt>n_var</dt>
<dd>total number of variants</dd>


<dt>max_cnt</dt>
<dd>maximum allele count, default 100</dd>

</dl>

get_ac_mat: get_ac_mat

Description

Usage

Value

Arguments

Examples