hum_j_df


human germline v gene segments. When multiple alleles were present, the
first one was included. These names and sequences can be changed by
customized by changing this dataframe. Additionally, repeating elements
can give certain germline gene elements a larger probability of being used
during repertoire evolution.


datasets

Simulation methods for the evolution of antibody repertoires. The heavy chain variable region of both human and C57BL/6 mice can be simulated in a time-dependent fashion. Both single lineages using one set of V-, D-, and J-genes or full repertoires can be simulated. The algorithm begins with an initial VDJ recombination event, starting the first phylogenetic tree. Upon completion, the main loop of the algorithm begins, with each iteration representing one simulated time step. Various mutation events are possible at each time step, contributing to a diverse final repertoire.

hum_j_df: hum_j_df

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