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AlteredPQR (version 0.1.0)

Detection of Altered Protein Quantitative Relationships

Description

Inference of protein complex states from quantitative proteomics data. The package takes information on known stable protein interactions (i.e. protein components of the same complex) and assesses how protein quantitative ratios change between different conditions. It reports protein pairs for which relative protein quantities to each other have been significantly altered in the tested condition.

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Version

Install

install.packages('AlteredPQR')

Monthly Downloads

384

Version

0.1.0

License

GPL (>= 3)

Maintainer

Marija Buljan

Last Published

June 10th, 2023

Functions in AlteredPQR (0.1.0)

CorShift

Changes in correlation trends
AlteredPQR_RB

Identification of outlier log ratios in quantitative proteomic measurements for investigated protein pairs.
quant_data_all

Proteomic measurements data matrix
int_pairs

Protein pairs