In this version of HIPAM, called $HIPAM_{MO}$, there are two different stopping criteria: First, if $|P| leq 2$, then P is a terminal node. If not, the second stopping criteria uses the Mean Split Silhouette. See Vinue et al. (2013) for more details.
The foundation and performance of the HIPAM algorithm is explained in hipamAnthropom
.
checkBranchLocalMO(tree,x,i,maxsplit,asw.tol,local.const,orness,type,...)
WeightsMixtureUB
and GetDistMatrix
.Wit, E., and McClure, J., (2004). Statistics for Microarrays: Design, Analysis and Inference. John Wiley & Sons, Ltd.
Wit, E., and McClure, J., (2006). Statistics for Microarrays: Inference, Design and Analysis. R package version 0.1.
Pollard, K. S., and van der Laan, M. J., (2002). A method to identify significant clusters in gene expression data. Vol. II of SCI2002 Proceedings, 318--325.
hipamAnthropom