aa_cdr3_dist: Average frequency of nucleotide mutations resulting in amino acid substitution in CDR3
Description
Calculate average frequency of nucleotide mutations resulting in amino acid substitution in CDR3.
Usage
aa_cdr3_dist(data)
Arguments
data
A column CDR3_IMGT from IMGT/HighV-Quest table 7 called "7_V-REGION-mutation-and-AA-change-table.txt"
Value
Output is the data matrix of average frequency of nucleotide mutations resulting in amino acid substitution.
References
Zuckerman NS., Hazanov H., Barak M., Edelman H., Hess S., Shcolnik H., Dunn-Walters D.,and Mehr R. Somatic hypermutation and antigen-driven selection of B cells are altered inautoimmune diseases.J Autoimmun, 35(4):325 - 335, 2010. doi: 10.1016/j.jaut.2010.07.004.