BE (version 0.2.4)

powcv: Power using coefficient of variation (CV)

Description

It calculates power for the bioequivalence test on ratio using coefficient of variation (CV).

Usage

powcv(n, CV, DesignNo = 1, True.R = 1, Alpha = 0.1, ThetaL = 0.8, ThetaU = 1.25)

Value

Returns power [0, 1)

Arguments

n

Sample size, n per group

CV

Coefficient of Variation (%)

DesignNo

Crossover design number.

  
 Design Number (treatment x sequence x period)
 1 2x2x2 : RT TR
 2 2x4x2 (Balaam Design) : TT RR RT TR 
 3 2x2x3 (Two-sequence Dual Design): TRR RTT 
 4 2x2x4 : TRRT RTTR
 5 2x4x4 : TTRR RRTT TRRT RTTR
 6 3x6x3 (William Design for 3 treatments) + carry-over effect 
         : RBA ARB BAR ABR BRA RAB
 7 3x6x3 (William Design for 3 treatments) - carry-over effect 
         : RBA ARB BAR ABR BRA RAB
 8 4x4x4 (William Design for 4 treatments) + carry-over effect 
         : RCAB ARBC BACR CBRA
 9 4x4x4 (William Design for 4 treatments) - carry-over effect 
         : RCAB ARBC BACR CBRA 

True.R

True ratio of test/reference

Alpha

Alpha error level

ThetaL

Lower limit of equivalence criteria

ThetaU

Upper limit of equivalence criteria

Author

Kyun-Seop Bae <[e-mail]>

Details

It calculates power of sample size (n per group) with CV.

Examples

powcv(12, 25)