get.abs_tval

value

lambda

zero.add2

<p>Return absolute t-value, used in optimization call in
<code><a rd-options="" href="/link/optim.boxcox?package=BIGL&version=1.5.3" data-mini-rdoc="BIGL::optim.boxcox">optim.boxcox</a></code></p>

Response surface methods for drug synergy analysis. Available
methods include generalized and classical Loewe formulations as well as Highest
Single Agent methodology. Response surfaces can be plotted in an interactive
3-D plot and formal statistical tests for presence of synergistic effects are
available. Implemented methods and tests are described in the article
"BIGL: Biochemically Intuitive Generalized Loewe null model for prediction
of the expected combined effect compatible with partial agonism and antagonism"
by Koen Van der Borght, Annelies Tourny, Rytis Bagdziunas, Olivier Thas,
Maxim Nazarov, Heather Turner, Bie Verbist & Hugo Ceulemans (2017)
<doi:10.1038/s41598-017-18068-5>.

Maxim Nazarov

BIGL

Biochemically Intuitive Generalized Loewe Model

get.abs_tval function

<p>Return absolute t-value, used in optimization call in
<code><a rd-options='' href='optim.boxcox'>optim.boxcox</a></code></p>

Return absolute t-value, used in optimization call in
<code><a rd-options='' href='optim.boxcox'>optim.boxcox</a></code> — get.abs_tval

Return absolute t-value, used in optimization call in
<code><a rd-options='' href='optim.boxcox'>optim.boxcox</a></code>

Return absolute t-value, used in optimization call in
<code><a rd-options="" href="/link/optim.boxcox?package=BIGL&version=1.5.3" data-mini-rdoc="BIGL::optim.boxcox">optim.boxcox</a></code>

get.abs_tval: Return absolute t-value, used in optimization call in `optim.boxcox`

Description

Usage

Arguments