plot.BIGLconfInt

Plot confidence intervals in a contour plot

Response surface methods for drug synergy analysis. Available
methods include generalized and classical Loewe formulations as well as Highest
Single Agent methodology. Response surfaces can be plotted in an interactive
3-D plot and formal statistical tests for presence of synergistic effects are
available. Implemented methods and tests are described in the article
"BIGL: Biochemically Intuitive Generalized Loewe null model for prediction
of the expected combined effect compatible with partial agonism and antagonism"
by Koen Van der Borght, Annelies Tourny, Rytis Bagdziunas, Olivier Thas,
Maxim Nazarov, Heather Turner, Bie Verbist & Hugo Ceulemans (2017)
<doi:10.1038/s41598-017-18068-5>.

Kathy Mutambanengwe

BIGL

Biochemically Intuitive Generalized Loewe Model

Heather Turner

Annelies Tourny

Olivier Thas

Maxim Nazarov

Rytis Bagdziunas

Stijn Hawinkel

plot.BIGLconfInt function

<dl><dt>x</dt>
<dd>off axis confidence intervals, a data frame</dd>
<dt>color</dt>
<dd>analysis with which to colour cells, either <code>effect-size</code> or <code>maxR</code></dd>
<dt>showAll</dt>
<dd>show all intervals in the plot or only significant ones, logical defaulting to <code>TRUE</code></dd>
<dt>digits</dt>
<dd>Numeric value indicating the number of digits used for numeric values</dd>
<dt>xlab</dt>
<dd>String for the x axis label</dd>
<dt>ylab</dt>
<dd>String for the y axis label</dd>
<dt>greyScale</dt>
<dd>If <code>greyScale = TRUE</code>, then plot is in grey scale,
otherwise in colour.</dd>
<dt>size</dt>
<dd>font size</dd>
<dt>...</dt>
<dd>additional arguments</dd></dl>

Arguments

Plot confidence intervals in a contour plot — plot.BIGLconfInt

<dl>

<dt>x</dt>
<dd>off axis confidence intervals, a data frame</dd>


<dt>color</dt>
<dd>analysis with which to colour cells, either <code>effect-size</code> or <code>maxR</code></dd>


<dt>showAll</dt>
<dd>show all intervals in the plot or only significant ones, logical defaulting to <code>TRUE</code></dd>


<dt>digits</dt>
<dd>Numeric value indicating the number of digits used for numeric values</dd>


<dt>xlab</dt>
<dd>String for the x axis label</dd>


<dt>ylab</dt>
<dd>String for the y axis label</dd>


<dt>greyScale</dt>
<dd>If <code>greyScale = TRUE</code>, then plot is in grey scale,
otherwise in colour.</dd>


<dt>size</dt>
<dd>font size</dd>


<dt>...</dt>
<dd>additional arguments</dd>

</dl>

plot.BIGLconfInt: Plot confidence intervals in a contour plot

Description

Usage

Arguments