Predict the entire response surface, so including on-axis points, and return the result as a matrix. For plotting purposes.
predictResponseSurface(
doseGrid,
fitResult,
null_model,
transforms = fitResult$transforms
)
A dose grid with unique combination of doses
Monotherapy (on-axis) model fit, e.g. produced by
fitMarginals
. It has to be a "MarginalFit"
object or a
list containing df
, sigma
, coef
,
shared_asymptote
and method
elements for, respectively,
marginal model degrees of freedom, residual standard deviation, named
vector of coefficient estimates, logical value of whether shared asymptote
is imposed and method for estimating marginal models during bootstrapping
(see fitMarginals
). If biological and power transformations
were used in marginal model estimation, fitResult
should contain
transforms
elements with these transformations. Alternatively, these
can also be specified via transforms
argument.
Specified null model for the expected response surface.
Currently, allowed options are "loewe"
for generalized Loewe model,
"hsa"
for Highest Single Agent model, "bliss"
for Bliss additivity,
and "loewe2"
for the alternative Loewe generalization.
Transformation functions. If non-null, transforms
is
a list containing 5 elements, namely biological and power transformations
along with their inverse functions and compositeArgs
which is a list
with argument values shared across the 4 functions. See vignette for more
information.