scaleResids

Functions for scaling, and rescaling residuals. May lead to unstable behaviour in practice

Response surface methods for drug synergy analysis. Available
methods include generalized and classical Loewe formulations as well as Highest
Single Agent methodology. Response surfaces can be plotted in an interactive
3-D plot and formal statistical tests for presence of synergistic effects are
available. Implemented methods and tests are described in the article
"BIGL: Biochemically Intuitive Generalized Loewe null model for prediction
of the expected combined effect compatible with partial agonism and antagonism"
by Koen Van der Borght, Annelies Tourny, Rytis Bagdziunas, Olivier Thas,
Maxim Nazarov, Heather Turner, Bie Verbist & Hugo Ceulemans (2017)
<doi:10.1038/s41598-017-18068-5>.

Kathy Mutambanengwe

BIGL

Biochemically Intuitive Generalized Loewe Model

Heather Turner

Annelies Tourny

Olivier Thas

Maxim Nazarov

Rytis Bagdziunas

Stijn Hawinkel

scaleResids function

<dl><dt>sampling_errors</dt>
<dd>A vector of raw residuals</dd>
<dt>...</dt>
<dd>passed on to predictVar</dd></dl>

Arguments

Functions for scaling, and rescaling residuals. May lead to unstable behaviour in practice — scaleResids

<dl>

<dt>sampling_errors</dt>
<dd>A vector of raw residuals</dd>


<dt>...</dt>
<dd>passed on to predictVar</dd>

</dl>

scaleResids: Functions for scaling, and rescaling residuals. May lead to unstable behaviour in practice

Description

Usage

Arguments

Details