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BasketTrial (version 0.1.0)

Bayesian Basket Trial Design and Analysis

Description

Provides tools for Bayesian basket trial design and analysis using a novel three-component local power prior framework with global borrowing control, pairwise similarity assessment and a borrowing threshold. Supports simulation-based evaluation of operating characteristics and comparison with other methods. Applicable to both equal and unequal sample size settings in early-phase oncology trials. For more details see Zhou et al. (2023) .

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Version

Install

install.packages('BasketTrial')

Monthly Downloads

342

Version

0.1.0

License

GPL-3

Maintainer

Haiming Zhou

Last Published

June 18th, 2025

Functions in BasketTrial (0.1.0)

get.weighted.power

Get Weighted Type I Error and Power.
JSD

JSD (Fujikawa et al., 2020) Method for Bayesian Basket Trial
post.infer

Posterior Inference for Simulated Basket Trial Data
Independent

Independent Beta Prior for Bayesian Basket Trial
generate.data

Generate Data for A Basket Trial Design
get.Q.bwer

Get Efficacy Cutoff based on Basket-Wise Error Rate (BWER) Control
localPP

Local Power Prior for Bayesian Basket Trial