BayesDA (version 2012.04-1)

meta: Results of 22 Clinical Trials of beta-Blockers

Description

Results of 22 clinical trials of beta-blockers for reducing mortality after myocardial infection. Used for meta-analysis.

Usage

data(meta)

Format

A data frame with 22 observations on the following 5 variables.

study

id code of study

control.deaths

number of deaths in control group

control.total

total number of patients in control group

treated.deaths

number of deaths in treatment group

treated.total

total number of patients in treatment group

Details

The 22 clinical trials each consist of two groups of heart attack patients randomly allocated to receive or not receive beta-blockers ( a family of drugs that affect the central nervous system and can relax the heart musckles).

Examples

data(meta)
names(meta)
# Calculating empirical log-odds and its sampling variances:
y <- apply(meta, 1, function(x) log( (x[4]/(x[5]-x[4]))/(x[2]/(x[3]-x[2])) ) )
s2 <- apply(meta, 1, function(x) 1/(x[5]-x[4]) + 1/x[4] +1/(x[3]-x[2]) + 1/x[2] )  
cbind("Study number"=meta[,1], "empirical log odds"=y, "empirical sampling variance of y"=s2)
#if(require(meta)){
#   funnel(y, sqrt(s2))
#   radial(y, sqrt(s2))
#}