Incidence of endometrial stromal polyps in \(k=70\) studys of female rats in control group of a 1977 study on the carcinogenic effects of a diabetic drug phenformin. For each of the \(k\) groups, \(y\) represents the number of rats who developed the tumors out of \(n\) total rats in the group.
data("rat")A data frame of \((y_i, n_i)\) for \(i = 1,...,70\).
ynumber of female rats in the \(i^{th}\) study who developed polyps/tumors
ntotal number of rats in the \(i^{th}\) study
Gelman, A., Carlin, J.B., Stern, H.S., Dunson, D.B., Vehtari, A., and Rubin, D.B., 2014. Bayesian Data Analysis (Vol. 3). Boca Raton, FL: CRC press.
Tarone, R.E., 1982. "The use of historical control information in testing for a trend in proportions," Biometrics, pp. 215-220.