CI_gamma1_evidence

Numeric vector of temperatures of power posteriors. One chain will be created for each element of the vector at the corresponding temperature.

temperatures

Numeric matrix of log probabilities of <code>y</code> at different temperatures (columns) in different iterations (rows).

y_log_lik_t_equals_1_traces

Numeric value of statistical confidence with which returning interval should contain the true value.

confidence

Integer value of number of simulations to use in estimation of the confidence interval.

simulations

Central limit theorem not applicable so use simulation to estimate confidence interval for evidence.

A fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - 'A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.

CI_gamma1_evidence: Estimate confidence interval for estimated marginal likelihood

Description

Usage

Arguments

Value