gamma0_evidence

Logical vector of case (<code>TRUE</code>) control (<code>FALSE</code>) status.

Beta shape hyper-priors for prior on rate of case labels

tau0_shape

Marginal probability calculated exactly by integration.

A fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - 'A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.

gamma0_evidence: Calculate marginal probability of observed case-control status y under model gamma = 0

Description

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See Also