prob_association

Logical value determining whether to return probabilities broken down by mode of inheritance.

by_model

Arguments to pass to <code><a rd-options="" href="/link/bevimed?package=BeviMed&version=5.3" data-mini-rdoc="BeviMed::bevimed">bevimed</a></code>.

Calculate probability of an association between case/control label and allele configuration, optionally broken down by mode of inheritance/model.

A fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - 'A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.

Daniel Greene

BeviMed

Bayesian Evaluation of Variant Involvement in Mendelian Disease

prob_association function

Arguments to pass to <code><a rd-options='' href='bevimed'>bevimed</a></code>.

prob_association: Calculate probability of association

Description

Usage

Arguments

Value

See Also