explaining_variants

Arguments to pass to <code><a rd-options="" href="/link/bevimed_m?package=BeviMed&version=5.8" data-mini-rdoc="BeviMed::bevimed_m">bevimed_m</a></code>.

Use <code><a rd-options="" href="/link/bevimed_m?package=BeviMed&version=5.8" data-mini-rdoc="BeviMed::bevimed_m">bevimed_m</a></code> to perform inference under model gamma = 1 and return only the expected number of pathogenic variants in cases.

A fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - 'A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.

Daniel Greene

BeviMed

Bayesian Evaluation of Variant Involvement in Mendelian Disease

explaining_variants function

Arguments to pass to <code><a rd-options='' href='bevimed_m'>bevimed_m</a></code>.

Use <code><a rd-options='' href='bevimed_m'>bevimed_m</a></code> to perform inference under model gamma = 1 and return only the expected number of pathogenic variants in cases.

explaining_variants: Calculate expected number of pathogenic variants in cases

Description

Usage

Arguments

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See Also