extract_explaining_variants

Object of class <code>x_BeviMed_m</code>. See function <code><a rd-options="" href="/link/bevimed_m?package=BeviMed&version=5.8" data-mini-rdoc="BeviMed::bevimed_m">bevimed_m</a></code>.

Extract expected number of variants involved in cases explained by pathogenic conigurations of alleles from <code>BeviMed_m</code> object.

A fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - 'A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.

Daniel Greene

BeviMed

Bayesian Evaluation of Variant Involvement in Mendelian Disease

extract_explaining_variants function

Object of class <code>x_BeviMed_m</code>. See function <code><a rd-options='' href='bevimed_m'>bevimed_m</a></code>.

extract_explaining_variants: Extract expected number of pathogenic variants in cases

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See Also