extract_conditional_prob_pathogenic

Extract the probability of pathogenicity for individual variants from a <code>BeviMed_m</code> object.

A fast integrative genetic association test for rare diseases based on a model for disease status given allele counts at rare variant sites. Probability of association, mode of inheritance and probability of pathogenicity for individual variants are all inferred in a Bayesian framework - 'A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases', Greene et al 2017 <doi:10.1016/j.ajhg.2017.05.015>.

Daniel Greene

BeviMed

Bayesian Evaluation of Variant Involvement in Mendelian Disease

extract_conditional_prob_pathogenic function

<dl><dt>x</dt>
<dd>Object of class <code>x_BeviMed_m</code>. See function <code>bevimed_m</code>.</dd></dl>

Arguments

Extract probability of pathogenicity for variant conditional on a given association model — extract_conditional_prob_pathogenic

<dl>

<dt>x</dt>
<dd>Object of class <code>x_BeviMed_m</code>. See function <code>bevimed_m</code>.</dd>

</dl>

extract_conditional_prob_pathogenic: Extract probability of pathogenicity for variant conditional on a given association model

Description

Usage

Value

Arguments

See Also