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BioNet (version 1.29.1)

Routines for the functional analysis of biological networks

Description

This package provides functions for the integrated analysis of protein-protein interaction networks and the detection of functional modules. Different datasets can be integrated into the network by assigning p-values of statistical tests to the nodes of the network. E.g. p-values obtained from the differential expression of the genes from an Affymetrix array are assigned to the nodes of the network. By fitting a beta-uniform mixture model and calculating scores from the p-values, overall scores of network regions can be calculated and an integer linear programming algorithm identifies the maximum scoring subnetwork.

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Version

1.29.1

License

GPL (>= 2)

Maintainer

Last Published

September 11th, 2015

Functions in BioNet (1.29.1)