aggrPvals


Numeric matrix of p-values, columns represent different sets of p-values


pval.matrix


Numeric constant, the order statistic that is used for the aggregation.


order


Boolean value whether to plot p-value distributions.


plot


The function aggregates several p-values into one p-value of p-values based on the order 
statistics of p-values. An overall p-value is given by the <em>i</em>th order statistic.


This package provides functions for the integrated
analysis of protein-protein interaction networks and the
detection of functional modules. Different datasets can be
integrated into the network by assigning p-values of
statistical tests to the nodes of the network. E.g. p-values
obtained from the differential expression of the genes from an
Affymetrix array are assigned to the nodes of the network. By
fitting a beta-uniform mixture model and calculating scores
from the p-values, overall scores of network regions can be
calculated and an integer linear programming algorithm
identifies the maximum scoring subnetwork.

Marcus Dittrich

BioNet

Routines for the functional analysis of biological networks

aggrPvals function

Numeric matrix of p-values, columns represent different sets of p-values

Numeric constant, the order statistic that is used for the aggregation.

Boolean value whether to plot p-value distributions.

The function aggregates several p-values into one p-value of p-values based on the order 
statistics of p-values. An overall p-value is given by the <em>i</em>th order statistic.

aggrPvals: Aggregate several p-values into one p-value

Description

Usage

Arguments

Value

Examples