CalculateSCCellProportions

Expression Set with single-cell data

sc.eset

A character string. Name of phenoData attribute in 
sc.eset that indicates individual ID.

subject.names

A character string. Name of phenoData attribute in sc.eset
that indicates cell type

cell.types

Returns proportion of each cell type out of total cells for each individual
in the single-cell Expression Set

Provides tools to accurately estimate cell type abundances
from heterogeneous bulk expression. A reference-based method utilizes
single-cell information to generate a signature matrix and transformation
of bulk expression for accurate regression based estimates. A marker-based
method utilizes known cell-specific marker genes to measure relative
abundances across samples.
For more details, see Jew and Alvarez et al (2019) <doi:10.1101/669911>.

CalculateSCCellProportions: Calculate cell proportions based on single-cell data

Description

Usage

Arguments

Value