Generalized Pairwise Comparisons
Description
Implementation of the Generalized Pairwise Comparisons (GPC). GPC
compare two groups of observations (intervention vs. control
group) regarding several prioritized endpoints. The net benefit
and win ratio statistics can then be estimated and corresponding
confidence intervals and p-values can be estimated using
resampling methods or the asymptotic U-statistic theory. The software enables the use of thresholds of
minimal important difference as well as stratification. Censored observations
can be handled using Gehan's modification of the Wilcoxon statistic, inverse
probability of censoring weights, or, in the case of right
censoring, using the empirical survival curves in each group to
estimating the expected score of the censored pairs.