S4BuyseTest-update

update,S4BuyseTest-method

Re-run Generalized Pairwise Comparisons (GPC) between two groups.

methods

Implementation of the Generalized Pairwise Comparisons (GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for complete observations, and extended in Peron (2018) <doi:10.1177/0962280216658320> to deal with right-censoring. GPC compare two groups of observations (intervention vs. control group) regarding several prioritized endpoints to estimate the probability that a random observation drawn from one group performs better/worse/equivalently than a random observation drawn from the other group. Summary statistics such as the net treatment benefit, win ratio, or win odds are then deduced from these probabilities. Confidence intervals and p-values are obtained based on asymptotic results (Ozenne 2021 <doi:10.1177/09622802211037067>), non-parametric bootstrap, or permutations. The software enables the use of thresholds of minimal importance difference, stratification, non-prioritized endpoints (O Brien test), and can handle right-censoring and competing-risks.

Brice Ozenne

BuyseTest

Generalized Pairwise Comparisons

Eva Cantagallo

William Anderson

Julien Peron

Johan Verbeeck

S4BuyseTest-update function

<dl><dt>object</dt>
<dd>an R object of class <code>S4BuyseTest</code>, i.e., output of <code>BuyseTest</code></dd>
<dt>...</dt>
<dd>additional arguments to the call, or arguments with changed values.</dd></dl>

Arguments

Author

Re-run two-group GPC — S4BuyseTest-update

<dl>

<dt>object</dt>
<dd>an R object of class <code>S4BuyseTest</code>, i.e., output of <code>BuyseTest</code></dd>


<dt>...</dt>
<dd>additional arguments to the call, or arguments with changed values.</dd>

</dl>

S4BuyseTest-update: Re-run two-group GPC

Description

Usage

Value

Arguments

Author