CARM-package

CARM

The CARM package provides functions to implement covariate-adjusted
adaptive randomization based on Mahalanobis distance.

In randomized controlled trial (RCT), balancing covariate is often one of the most important concern. CARM package provides functions to balance the covariates and generate allocation sequence by covariate-adjusted Adaptive Randomization via Mahalanobis-distance (ARM) for RCT. About what ARM is and how it works please see Y. Qin, Y. Li, W. Ma, H. Yang, and F. Hu (2024). "Adaptive randomization via Mahalanobis distance" Statistica Sinica. <doi:10.5705/ss.202020.0440>. In addition, the package is also suitable for the randomization process of multi-arm trials. For details, please see Yang H, Qin Y, Wang F, et al. (2023). "Balancing covariates in multi-arm trials via adaptive randomization" Computational Statistics & Data Analysis.<doi:10.1016/j.csda.2022.107642>.

Fanglu Chen

Covariate-Adjusted Adaptive Randomization via
Mahalanobis-Distance

Haoyu Yang

Yichen Qin

Yang Li

CARM-package function

See <code>ARM()</code>, <code>ARMM()</code>, and <code>stratum_ARM()</code> for usage details.

Randomization functions

Maintainer: Fanglu Chen <a href="/link/chenfanglu1031%40qq.com?package=CARM&version=2.0.0" data-mini-rdoc="CARM::chenfanglu1031@qq.com">chenfanglu1031@qq.com</a>
Authors:<ul>
<li>Haoyu Yang <a href="/link/haoyuyang%40ruc.edu.cn?package=CARM&version=2.0.0" data-mini-rdoc="CARM::haoyuyang@ruc.edu.cn">haoyuyang@ruc.edu.cn</a></li>
<li>Yichen Qin <a href="/link/qinyn%40ucmail.uc.edu?package=CARM&version=2.0.0" data-mini-rdoc="CARM::qinyn@ucmail.uc.edu">qinyn@ucmail.uc.edu</a></li>
<li>Yang Li <a href="/link/yang.li%40ruc.edu.cn?package=CARM&version=2.0.0" data-mini-rdoc="CARM::yang.li@ruc.edu.cn">yang.li@ruc.edu.cn</a></li>
</ul>

Author

CARM: Covariate-adjusted Adaptive Randomization via Mahalanobis distance — CARM-package

See <code>ARM()</code>, <code>ARMM()</code>, and <code>stratum_ARM()</code> for usage details.

Maintainer: Fanglu Chen <a href='mailto:chenfanglu1031@qq.com'>chenfanglu1031@qq.com</a>
Authors:<ul>
<li>Haoyu Yang <a href='mailto:haoyuyang@ruc.edu.cn'>haoyuyang@ruc.edu.cn</a></li>
<li>Yichen Qin <a href='mailto:qinyn@ucmail.uc.edu'>qinyn@ucmail.uc.edu</a></li>
<li>Yang Li <a href='mailto:yang.li@ruc.edu.cn'>yang.li@ruc.edu.cn</a></li>
</ul>

CARM-package: CARM: Covariate-adjusted Adaptive Randomization via Mahalanobis distance

Description

Arguments

Randomization functions

Author