CAnD (version 1.4.0)

calc_combP: Calculate the Combined CAnD Test Statistic P-value

Description

Calculate the combined CAnD test statistic p-value on a set of ancestry proportions estimated for a particular ancestral subpopulation of interest

Usage

calc_combP(chrAncest)

Arguments

chrAncest

A data.frame holding the ancestral proportions; each row corresponds to a sample and each column corresponds to a chromosomal/chromosomal segment ancestry proportion. Note: only include the proportions for one ancestral population at a time.

Value

A vector of length two where `statistic' is the combined CAnD statistic and `pvalue' is it's corresponding p-value, where the combined statistic is combined over all chromosomes/chromosomal segments included in chrAncest.

References

McHugh, C., Brown, L., Thornton, T. Detecting heterogeneity in population structure across chromosomes in admixed populations. Manuscript in Preparation.

Examples

data(ancestries)
euroCols <- grep("Euro",colnames(ancestries))
euro <- ancestries[,euroCols]
res <- calc_combP(euro)
res