get_CPM

A function to normalize sgRNA read counts.

Provides functions for hit gene identification and quantification of sgRNA (single-guided RNA) abundances for CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) pooled screen data analysis.
Details are in Jeong et al. (2019) <doi:10.1101/gr.245571.118> and Baggerly et al. (2003) <doi:10.1093/bioinformatics/btg173>.

Hyun-Hwan Jeong

CRISPR Pooled Screen Analysis using Beta-Binomial Test

get_CPM function

<dl><dt>sgcount</dt>
<dd>The input table contains read counts of sgRNAs for each sample
A function to calculate the CPM (Counts Per Million) (required)</dd></dl>

Arguments

A function to normalize sgRNA read counts. — get_CPM

<dl>

<dt>sgcount</dt>
<dd>The input table contains read counts of sgRNAs for each sample
A function to calculate the CPM (Counts Per Million) (required)</dd>

</dl>

get_CPM: A function to normalize sgRNA read counts.

Description

Usage

Value

Arguments

Examples