referenceReadCounts

Synthetic reference data set of simulated read counts.
    Only to be used for code examples.

datasets

A method that allows for the use of a collection of non-matched
normal tissue samples. Our approach uses a non-parametric bootstrap
subsampling of the available reference samples to estimate the distribution
of read counts from targeted sequencing. As inspired by random forest, this
is combined with a procedure that subsamples the amplicons associated with
each of the targeted genes. The obtained information allows us to reliably
classify the copy number aberrations on the gene level.

Thomas Wolf

CNVPanelizer

Reliable CNV detection in targeted sequencing applications

referenceReadCounts function

A matrix with columns identifying the sample names and
columns the gene names

referenceReadCounts: Reference sample data

Description

Usage

Arguments

Value

format

source