segmentSamplesUsingPopInformation:
Implement the segmentation process for multiple populations
Description
Segment read-count windows into region having similar signal values by
using the DNAcopy package (Venkatraman and Olshen, 2007) and refine this process
to obtain segmentation scores at genes. Then, the function adjusts segmentation scores
for multiple populations using a linear regression model.
Usage
segmentSamplesUsingPopInformation(Object, ...)
Arguments
Object
An object of class CNVrd2.
...
Optional arguments.
Value
segmentationScores
All adjusted results of the segmentation process.
segmentationScoresFromSinglePops
Segmentation scores of single populations.
segmentResults
Un-adjusted segmentation scores
observedReadCountRatios
Observed read-count ratios of genes. This value is a matrix of observed read-count ratios at genes if (only inputBamFile = TRUE).
stdCntMatrix
Matrix of read counts (standardized).
References
Venkatraman, E., Olshen, A. B., 2007. A faster circular binary segmentation algorithm for the analysis of array chg data. Bioinformatics 23 (6), 657-663.