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CNVrd2 (version 1.10.2)

segmentSamplesUsingPopInformation: Implement the segmentation process for multiple populations

Description

Segment read-count windows into region having similar signal values by using the DNAcopy package (Venkatraman and Olshen, 2007) and refine this process to obtain segmentation scores at genes. Then, the function adjusts segmentation scores for multiple populations using a linear regression model.

Usage

segmentSamplesUsingPopInformation(Object, ...)

Arguments

Object
An object of class CNVrd2.
...
Optional arguments.

Value

segmentationScores
All adjusted results of the segmentation process.
segmentationScoresFromSinglePops
Segmentation scores of single populations.
segmentResults
Un-adjusted segmentation scores
observedReadCountRatios
Observed read-count ratios of genes. This value is a matrix of observed read-count ratios at genes if (only inputBamFile = TRUE).
stdCntMatrix
Matrix of read counts (standardized).

References

Venkatraman, E., Olshen, A. B., 2007. A faster circular binary segmentation algorithm for the analysis of array chg data. Bioinformatics 23 (6), 657-663.

See Also

countReadInWindow, DNAcopy