A Combined Association Test for Genes using Summary Statistics
To compute gene-based genetic association statistics from P values at multiple SNPs and genotype data of ancestry matched reference samples. COMBined Association Test (COMBAT) incorporates strengths from multiple existing gene-based tests, including VEGAS, GATES and SimpleM, and achieves much improved performance than any individual test.
Functions in COMBAT
|COMBAT||A Combined Gene-based Association Test|
|ext_simes||Calling Gene-based Association Tests|
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