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CONDOP (version 1.0)

detect.sid.points: Find strat/end transcription points.

Description

Internal function to identify the boundaries of transcriptionally active regions using a sliding window algorithm. The sliding window algorithm uses fixed windows with a length of 100 nt that slides across the coverage-depth data table and finds segments of coverage depth highly and statistically correlated with a vector of 100 integers modeling a simple shape of sharp increases (or decreases) in transcription: x =???[0..0,1..1] (or x =???[1..1,0..0])).

Usage

detect.sid.points(cd, sizeWindow, verbose = TRUE)

Arguments

cd
A data table containing the coverage depth of an RNA-seq expression profile(s).
sizeWindow
An annotation data table.
verbose

Details

With default values, segments having a positive correlation coefficient (exceeding 0.7) and a significant correlation test p-value (