gen_true_RHO

Simulates cell type proportions under three scenarios.

Perform bulk and cell type-specific expression quantitative trail loci mapping with our novel method (Little et al. (2023) <doi:10.1038/s41467-023-38795-w>).

Paul Little

CSeQTL

Cell Type-Specific Expression Quantitative Trail Loci Mapping

gen_true_RHO function

<dl><dt>wRHO</dt>
<dd>An integer taking values 1, 2, or 3 for one of the three
scenarios. For <code>wRHO</code> equal to 2 or 3, <code>QQ</code> needs to be 
set to 3 cell types.</dd>
<dt>NN</dt>
<dd>Positive integer for sample size.</dd>
<dt>QQ</dt>
<dd>Positive integer for number of cell types.</dd>
<dt>RHO</dt>
<dd>Default to <code>NULL</code> leads to simulating cell 
type proportions. If a matrix of proportions is supplied, 
this function will append row/column names.</dd></dl>

Arguments

gen_true_RHO — gen_true_RHO

<dl>

<dt>wRHO</dt>
<dd>An integer taking values 1, 2, or 3 for one of the three
scenarios. For <code>wRHO</code> equal to 2 or 3, <code>QQ</code> needs to be 
set to 3 cell types.</dd>


<dt>NN</dt>
<dd>Positive integer for sample size.</dd>


<dt>QQ</dt>
<dd>Positive integer for number of cell types.</dd>


<dt>RHO</dt>
<dd>Default to <code>NULL</code> leads to simulating cell 
type proportions. If a matrix of proportions is supplied, 
this function will append row/column names.</dd>

</dl>

gen_true_RHO: gen_true_RHO

Description

Usage

Value

Arguments