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CVEK (version 0.1-2)

compute_info: Computing Information Matrices

Description

Compute information matrices based on block matrices.

Usage

compute_info(P0_mat, mat_del = NULL, mat_sigma2 = NULL, mat_tau = NULL)

Arguments

P0_mat

(matrix, n*n) Scale projection matrix under REML.

mat_del

(matrix, n*n) Derivative of the scale covariance matrix of Y with respect to delta.

mat_sigma2

(matrix, n*n) Derivative of the scale covariance matrix of Y with respect to sigma2.

mat_tau

(matrix, n*n) Derivative of the scale covariance matrix of Y with respect to tau.

Value

I0

(matrix, n*n) The computed information value.

Details

This function gives the information value of the interaction strength.

References

Arnab Maity and Xihong Lin. Powerful tests for detecting a gene effect in the presence of possible gene-gene interactions using garrote kernel machines. December 2011.