ExtraDoseItem-class

ExtraDoseItem

internal

Facilitate Pharmacokinetic (PK) and Pharmacodynamic (PD) modeling
and simulation with powerful tools for Nonlinear Mixed-Effects (NLME)
modeling. The package provides access to the same advanced Maximum Likelihood
algorithms used by the NLME-Engine in the Phoenix platform. These tools support
a range of analyses, from parametric methods to individual and pooled data, and
support integrated use within the Pirana pharmacometric workbench
<doi:10.1002/psp4.70067>. Execution is supported both locally or on
remote machines.

James Craig

Certara.RsNLME

Pharmacometric Modeling

Michael Tomashevskiy

Vitalii Nazarov

Shuhua Hu

Soltanshahi Fred

Certara USA, Inc. 

ExtraDoseItem-class function

<dl>
<dt><code>name</code></dt>
<dd>Dose point name</dd></dl>
<dt><code>type</code></dt>
<dd>Character; Options are "Bolus" or "Infusion"</dd>
<dt><code>amount</code></dt>
<dd>Optional; Character specifying corresponding column in data or numeric specifying dose amount</dd>
<dt><code>rate</code></dt>
<dd>Optional; Character specifying corresponding column in data or numeric specifying dose rate</dd>
<dt><code>deltaTime</code></dt>
<dd>Optional; Character specifying corresponding column in data or numeric specifying delta time</dd>
<dt><code>isSecondDose</code></dt>
<dd>Use second dose point on compartment?</dd>
<dt><code>data</code></dt>
<dd>Optional data frame. Must specify <code>data</code> if supplying column as character value to <code>amount, rate, deltaTime</code> arguments</dd>

Slots

Defines an extra dose point — ExtraDoseItem-class

<dl>
<dt><code>name</code></dt>
<dd>Dose point name</dd>


<dt><code>type</code></dt>
<dd>Character; Options are "Bolus" or "Infusion"</dd>


<dt><code>amount</code></dt>
<dd>Optional; Character specifying corresponding column in data or numeric specifying dose amount</dd>


<dt><code>rate</code></dt>
<dd>Optional; Character specifying corresponding column in data or numeric specifying dose rate</dd>


<dt><code>deltaTime</code></dt>
<dd>Optional; Character specifying corresponding column in data or numeric specifying delta time</dd>


<dt><code>isSecondDose</code></dt>
<dd>Use second dose point on compartment?</dd>


<dt><code>data</code></dt>
<dd>Optional data frame. Must specify <code>data</code> if supplying column as character value to <code>amount, rate, deltaTime</code> arguments</dd>


</dl>

Defines an extra dose point

ExtraDoseItem-class: Defines an extra dose point

Description

Arguments

Slots